TV6 and PDGFRB: a license to fuse.
نویسندگان
چکیده
منابع مشابه
AN EFFICIENT METHOD FOR OPTIMUM PERFORMANCE-BASED SEISMIC DESIGN OF FUSED BUILDING STRUCTURES
A dual structural fused system consists of replaceable ductile elements (fuses) that sustain major seismic damage and leave the primary structure (PS) virtually undamaged. The seismic performance of a fused structural system is determined by the combined behavior of the individual PS and fuse components. In order to design a feasible and economic structural fuse concept, we need a procedure to ...
متن کاملExperimental Study of Breaching of an Earthen Dam using a Fuse Plug Model
Failure of dams due to overtopping is among the most frequent forms of embankment failures. Owing to massive and wide spread damage to structures and loss of lives associated with a dam failure, the subject has drawn the attention of scientists. The study also becomes essential for damage assessment and for development of early warning system of people downstream of the embankment. The rate of ...
متن کاملAn Online Free Penetration Multi-Stage Fuse Saving Protection Scheme in Distribution Systems with Photovoltaic Sources
In this paper, a multi-stage protective scheme is proposed to maintain the fuse and reclosers coordination. The proposed method operates online and proportional to the photovoltaic sources penetration rate. In the first step, a non-standard Current - Time - Voltage curve is used for fuse saving. If the new calculated TDS from the first stage is not implementable to the reclosers, the second sta...
متن کاملCharacterization of three new imatinib-responsive fusion genes in chronic myeloproliferative disorders generated by disruption of the platelet-derived growth factor receptor beta gene.
BACKGROUND AND OBJECTIVES We sought to identify new fusion genes with involvement of the platelet-derived growth factor receptor beta gene (PDGFRB) in three patients presenting with various subtypes of chronic myeloproliferative disorders associated with chromosomal aberrations involving chromosome bands 5q31-33. DESIGN AND METHODS We performed 5 rapid amplification of cDNA ends (5 -RACE)-pol...
متن کاملAcute Lymphoblastic Leukemia Patient with Variant ATF7IP/PDGFRB Fusion and Favorable Response to Tyrosine Kinase Inhibitor Treatment: A Case Report
BACKGROUND Chromosomal translocations involving the PDGFRB gene have been reported in a broad spectrum of hematological malignancies. An ATF7IP/PDGFRB fusion was recently identified in a Philadelphia chromosome-like (Ph-like) B-progenitor acute lymphoblastic leukemia (B-ALL) patient. Here we report on a special case of a Ph-like ALL patient who had a variant ATF7IP/PDGFRB fusion. CASE REPORT In...
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عنوان ژورنال:
- Haematologica
دوره 92 2 شماره
صفحات -
تاریخ انتشار 2007